CD45RA+ and CD45RO+ lymphocyte subpopulations in patients with monoclonal gammopathies: correlations with diagnosis, clinical stage and treatment status.

نویسندگان

  • José María Raya Sánchez
  • Luis Hernández Nieto
  • María Luisa Brito Barroso
  • Gloria González Brito
  • María del Mar Caballero Gómez
چکیده

Alterations in blood lymphocyte subsets may be involved in the development of overt myeloma. Naive (CD4+CD45RA+) and memory (CD4+CD45RO+) helper T-cell subsets are important effectors of immune T-cell regulation. We analyzed the distribution of these blood lymphocyte subpopulations in patients with monoclonal gammopathies, considering the type of disorder, clinical stage, and treatment status.

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عنوان ژورنال:
  • Haematologica

دوره 89 6  شماره 

صفحات  -

تاریخ انتشار 2004